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USMLE Step 1 Prep Course (Step 1)
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USMLE Step 1 Prep Course (Step 1)

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DNA Replication And Repair
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Course Overview
Chapters 9
Lessons 90
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9
Chapters
90
Lessons
—
Questions
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First Lesson

Course Outline

1 Biochemistry And Genetics 12 lessons ▾
1.1 — Molecular Biology Foundations
1.1.1 DNA Replication And Repair Preview
1.1.2 Transcription And RNA Processing Locked
1.1.3 Translation And Genetic Code Locked
1.2 — Metabolism And Energy Pathways
1.2.1 Glycolysis And Gluconeogenesis Locked
1.2.2 TCA Cycle And Oxidative Phosphorylation Locked
1.2.3 Lipid And Ketone Metabolism Locked
1.3 — Genetic Principles And Disorders
1.3.1 Inheritance Patterns And Pedigrees Locked
1.3.2 Chromosomal And Trinucleotide Disorders Locked
1.3.3 Population Genetics And Screening Locked
1.4 — Nutrition And Molecular Disorders
1.4.1 Vitamin Deficiency Syndromes Locked
1.4.2 Lysosomal And Glycogen Diseases Locked
1.4.3 Porphyrias And Heme Synthesis Locked
2 Cell Biology And Pathology 12 lessons ▾
2.1 — Cell Injury And Death
2.1.1 Cellular Adaptations Locked
2.1.2 Ischemic And Toxic Injury Locked
2.1.3 Apoptosis And Necrosis Patterns Locked
2.2 — Inflammation And Healing
2.2.1 Acute Inflammation Mediators Locked
2.2.2 Chronic Inflammation And Granulomas Locked
2.2.3 Wound Healing And Repair Locked
2.3 — Hemodynamics And Vascular Pathology
2.3.1 Edema And Hyperemia Locked
2.3.2 Thrombosis And Embolism Locked
2.3.3 Shock And Ischemia Syndromes Locked
2.4 — Neoplasia Principles
2.4.1 Oncogenes And Tumor Suppressors Locked
2.4.2 Tumor Progression And Metastasis Locked
2.4.3 Paraneoplastic And Cancer Syndromes Locked
3 Immunology And Microbiology 12 lessons ▾
3.1 — Innate And Adaptive Immunity
3.1.1 Immune Cells And Cytokines Locked
3.1.2 Antibody Structure And Function Locked
3.1.3 Hypersensitivity Reactions Locked
3.2 — Immunodeficiency And Autoimmunity
3.2.1 Primary Immunodeficiency Syndromes Locked
3.2.2 Autoantibodies And Tolerance Loss Locked
3.2.3 Transplant And Tumor Immunology Locked
3.3 — Bacteriology And Antimicrobials
3.3.1 Gram-Positive And Gram-Negative Patterns Locked
3.3.2 Bacterial Toxins And Virulence Locked
3.3.3 Antibacterial Drug Mechanisms Locked
3.4 — Virology Mycology And Parasitology
3.4.1 Viral Replication And Disease Locked
3.4.2 Fungal Pathogens And Mycoses Locked
3.4.3 Parasites And Protozoa Locked
4 Pharmacology Principles 9 lessons ▾
4.1 — Pharmacokinetics And Dynamics
4.1.1 Absorption Distribution Metabolism Excretion Locked
4.1.2 Dose Response Relationships Locked
4.1.3 Adverse Effects And Interactions Locked
4.2 — Autonomic Pharmacology
4.2.1 Cholinergic Receptors And Agonists Locked
4.2.2 Anticholinergics And Cholinesterase Inhibitors Locked
4.2.3 Adrenergic Agonists And Antagonists Locked
4.3 — Autacoids And Toxicology
4.3.1 NSAIDs And Acetaminophen Locked
4.3.2 Opioids And Sedative Toxicity Locked
4.3.3 Sympathomimetic And Antidote Syndromes Locked
5 Systems Foundations 9 lessons ▾
5.1 — Anatomy And Embryology
5.1.1 Embryologic Folding And Germ Layers Locked
5.1.2 Neural Crest And Congenital Syndromes Locked
5.1.3 High-Yield Lesion Localization Locked
5.2 — Physiology And Homeostasis
5.2.1 Membrane Transport And Potentials Locked
5.2.2 Fluid Compartments And Osmolality Locked
5.2.3 Acid Base Interpretation Locked
5.3 — Biostatistics And Ethics
5.3.1 Study Design And Bias Locked
5.3.2 Test Characteristics And Risk Locked
5.3.3 Ethics And Communication Principles Locked
6 Cardiopulmonary Systems 9 lessons ▾
6.1 — Cardiovascular Physiology And Pathology
6.1.1 Cardiac Cycle And Hemodynamics Locked
6.1.2 Ischemic And Valvular Disease Locked
6.1.3 Heart Failure And Arrhythmias Locked
6.2 — Pulmonary Physiology And Disease
6.2.1 Ventilation Perfusion And Gas Exchange Locked
6.2.2 Obstructive And Restrictive Patterns Locked
6.2.3 Pulmonary Infections And Vascular Disease Locked
6.3 — Cardiopulmonary Pharmacology
6.3.1 Antihypertensives And Diuretics Locked
6.3.2 Antianginal And Heart Failure Drugs Locked
6.3.3 Asthma And COPD Drugs Locked
7 Renal Endocrine Reproductive 9 lessons ▾
7.1 — Renal Physiology And Disorders
7.1.1 Glomerular And Tubular Function Locked
7.1.2 Electrolyte And Acid Base Disorders Locked
7.1.3 Nephritic Nephrotic And Tubular Disease Locked
7.2 — Endocrine Physiology And Pathology
7.2.1 Hormone Signaling And Feedback Locked
7.2.2 Pituitary Thyroid And Adrenal Disorders Locked
7.2.3 Diabetes And Calcium Homeostasis Locked
7.3 — Reproductive System And Pregnancy
7.3.1 Gonadal Hormones And Cycles Locked
7.3.2 Reproductive Pathology And Neoplasia Locked
7.3.3 Pregnancy And Teratology Locked
8 Gastrointestinal Musculoskeletal And Skin 9 lessons ▾
8.1 — Gastrointestinal And Hepatobiliary Disease
8.1.1 GI Physiology And Absorption Locked
8.1.2 Inflammatory And Malabsorptive Disorders Locked
8.1.3 Liver Pancreas And Biliary Disease Locked
8.2 — Musculoskeletal And Rheumatologic Disease
8.2.1 Bone Remodeling And Mineralization Locked
8.2.2 Arthritis And Connective Tissue Disorders Locked
8.2.3 Muscle Disease And Pharmacology Locked
8.3 — Dermatology And Connective Tissue
8.3.1 Skin Structure And Lesions Locked
8.3.2 Inflammatory And Blistering Disorders Locked
8.3.3 Pigment And Skin Cancer Disorders Locked
9 Nervous System And Hematology 9 lessons ▾
9.1 — Neuroanatomy And Neuroscience
9.1.1 Neurons Glia And Neurotransmitters Locked
9.1.2 Motor Sensory And Brainstem Pathways Locked
9.1.3 Cerebrovascular And Demyelinating Disease Locked
9.2 — Neurologic Disorders And Pharmacology
9.2.1 Seizure And Antiepileptic Drugs Locked
9.2.2 Movement Disorders And Basal Ganglia Locked
9.2.3 Neuromuscular Disorders And Junctions Locked
9.3 — Hematology And Oncology
9.3.1 Hematopoiesis And Red Cell Indices Locked
9.3.2 Anemias Leukemias And Lymphomas Locked
9.3.3 Coagulation And Transfusion Reactions Locked

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