COMLEX-USA Level 1 Exam Prep

COMLEX Level 1 Prep Course (Level 1)

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8
Chapters
72
Lessons
30
SME-Reviewed Items
500K+
Original Illustrations
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500,000+ Original Illustrations

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How MedExPrep compares
Feature-by-feature comparison with every major exam prep platform across all courses.*
Feature MedExPrep UWorld Kaplan Mometrix Princeton Review TrueLearn
Tutor Mode™ on Every Question
Tutor Mode™ on Every Lesson
Audio Lectures (No Extra Cost) Add-on*
Total Questions (All Courses) 5,000,000+ ~3,400/exam* ~2,000/exam* ~500/exam* ~1,500/exam* ~2,000/exam*
Original Illustrations 500,000+ Limited* Limited* Minimal* Limited* Some*
Free Weekly Webinars
Flashcards Included Add-on* Sold separately
Board-Certified Expert Content Varies*
NCCA / ACPE / ISO Aligned Varies* Varies* Varies* Varies*
Interview & Career Coaching
Multi-Exam / Multi-Field Coverage Select exams Select exams Many exams* Select exams Select exams
Free Preview (No Signup) Sample only Limited
Approx. Price Range* Lowest price
6-month full access
$319 – $719+ $1,999 – $4,000+ $99/mo
($594 for 6 mo)
$1,600 – $7,300+ $149 – $400+
* Comparison based on publicly available information as of 2025. Competitor features, pricing, and content volumes are approximate estimates and may vary by exam, subscription tier, and region. Trademarks belong to their respective owners. MedExPrep totals reflect aggregate content across all courses and exam categories.
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Course Outline — 8 Chapters, 72 Lessons
1 Biochemistry And Genetics 9 lessons
1.1 — Molecular Biology Foundations
1.1.1 DNA Replication And Repair Preview
1.1.2 Transcription And RNA Processing Locked
1.1.3 Translation And Protein Targeting Locked
1.2 — Metabolism And Nutrition
1.2.1 Glycolysis TCA And ETC Locked
1.2.2 Glycogen And Lipid Disorders Locked
1.2.3 Vitamins Minerals And Cofactors Locked
1.3 — Genetics And Genomics
1.3.1 Inheritance And Pedigree Patterns Locked
1.3.2 Population Genetics Principles Locked
1.3.3 Cytogenetics And Molecular Testing Locked
2 Immunology And Microbiology 9 lessons
2.1 — Innate And Adaptive Immunity
2.1.1 Immune Cells And Cytokines Locked
2.1.2 Hypersensitivity And Autoimmunity Locked
2.1.3 Primary Immunodeficiency Syndromes Locked
2.2 — Bacteriology And Antimicrobials
2.2.1 Gram Positive Pathogens Locked
2.2.2 Gram Negative And Atypicals Locked
2.2.3 Antibacterial Drug Mechanisms Locked
2.3 — Virology Mycology And Parasitology
2.3.1 DNA And RNA Viruses Locked
2.3.2 Systemic And Opportunistic Fungi Locked
2.3.3 Protozoa Helminths And Ectoparasites Locked
3 General Pathology And Pharmacology 9 lessons
3.1 — Cell Injury And Neoplasia
3.1.1 Cell Death And Adaptation Locked
3.1.2 Inflammation And Wound Repair Locked
3.1.3 Neoplasia And Tumor Biology Locked
3.2 — Autonomics And Core Pharmacology
3.2.1 Pharmacokinetics And Dynamics Locked
3.2.2 Autonomic Receptors And Signaling Locked
3.2.3 Autonomic Drug Prototypes Locked
3.3 — Hematology Oncology And Toxicology
3.3.1 Anemia And Coagulation Basics Locked
3.3.2 Antineoplastic Drug Mechanisms Locked
3.3.3 Common Toxidromes And Antidotes Locked
4 Cardiopulmonary Systems 9 lessons
4.1 — Cardiac Physiology And Pathology
4.1.1 Cardiac Cycle And Hemodynamics Locked
4.1.2 ECG Arrhythmia And Ischemia Locked
4.1.3 Valvular Disease And Heart Failure Locked
4.2 — Vascular Pharmacology And Hemostasis
4.2.1 Blood Pressure Regulation Mechanisms Locked
4.2.2 Cardiovascular Drug Classes Locked
4.2.3 Thrombosis And Vascular Disorders Locked
4.3 — Respiratory Physiology And Disease
4.3.1 Ventilation Perfusion And Gas Exchange Locked
4.3.2 Obstructive And Restrictive Patterns Locked
4.3.3 Pulmonary Vascular And Pleural Disease Locked
5 Renal Endocrine And Reproductive 9 lessons
5.1 — Renal Physiology And Disorders
5.1.1 Nephron Function And GFR Locked
5.1.2 Electrolyte And Acid Base Disorders Locked
5.1.3 Glomerular Tubular And Diuretic Syndromes Locked
5.2 — Endocrine Axes And Pharmacology
5.2.1 Hypothalamic Pituitary Thyroid Axis Locked
5.2.2 Adrenal Pancreatic And Calcium Regulation Locked
5.2.3 Integrated Endocrine Laboratory Patterns Locked
5.3 — Reproductive Embryology And Disease
5.3.1 Gametogenesis And Sexual Development Locked
5.3.2 Female Reproductive Pathology Locked
5.3.3 Male Reproductive Pathology Locked
6 Gastrointestinal Musculoskeletal And Skin 9 lessons
6.1 — GI Physiology And Hepatobiliary Disease
6.1.1 GI Secretion Absorption And Motility Locked
6.1.2 Liver Pancreas And Biliary Pathology Locked
6.1.3 GI Pharmacology And Inflammation Locked
6.2 — Bone Muscle And Rheumatology
6.2.1 Bone Remodeling And Mineralization Locked
6.2.2 Myopathies And Neuromuscular Junction Locked
6.2.3 Arthritis And Connective Tissue Disease Locked
6.3 — Dermatology And Soft Tissue
6.3.1 Skin Layers And Lesion Types Locked
6.3.2 Inflammatory And Autoimmune Dermatoses Locked
6.3.3 Skin Infections And Neoplasms Locked
7 Neuroscience And Behavior 9 lessons
7.1 — Neuroanatomy And Localization
7.1.1 CNS Pathways And Blood Supply Locked
7.1.2 Cranial Nerves And Special Senses Locked
7.1.3 Movement Seizure And Demyelinating Disorders Locked
7.2 — Psychiatry And Behavioral Science
7.2.1 Psychiatric Disorders And Defense Mechanisms Locked
7.2.2 Psychopharmacology And Adverse Effects Locked
7.2.3 Substance Use And Safety Locked
7.3 — Biostatistics Ethics And Public Health
7.3.1 Study Design And Bias Locked
7.3.2 Risk Statistics And Test Interpretation Locked
7.3.3 Ethics Professionalism And Quality Locked
8 Anatomy Embryology And OPP OMM 9 lessons
8.1 — Gross Anatomy And Embryology
8.1.1 Thorax Abdomen And Pelvis Anatomy Locked
8.1.2 Upper And Lower Limb Anatomy Locked
8.1.3 Head Neck And Neuroembryology Locked
8.2 — Osteopathic Principles And Diagnosis
8.2.1 Osteopathic Tenets And Somatic Dysfunction Locked
8.2.2 Spinal Rib And Pelvic Diagnosis Locked
8.2.3 Sacral And Cranial Foundations Locked
8.3 — Viscerosomatic Chapman And OMT Safety
8.3.1 Viscerosomatic And Facilitated Segments Locked
8.3.2 Chapman Points And Lymphatics Locked
8.3.3 OMT Indications Contraindications And Integration Locked

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