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Patient Safety, Data Integrity, and GCP: The Three Pillars of Trial Success

  • 69 minutes
  • 36 slides
What we'll cover
  • 0:00 Why The Pillars Matter
  • 8:00 Patient Safety In Practice
  • 18:00 Data Integrity At Source
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What you'll take away

Practical shifts you can apply this week

  • Identify Operational Links

    See how one weak handoff can affect subject protection, data credibility, and compliance at once.

  • Evaluate Trial Decisions

    Judge routine choices by their downstream effect on patients, records, and inspection risk.

  • Diagnose Early Warning Signals

    Spot small quality breaks before they turn into safety events, findings, or unusable data.

  • Apply A Risk-Based Framework

    Use practical controls across sites, sponsors, and vendors where the risk is actually highest.

  • Draft Immediate Next-Step Actions

    Leave with a short action plan you can use to improve trial quality and inspection readiness.

Agenda

What we'll cover

  1. 0:00

    Why The Pillars Matter

    How patient safety, data integrity, and GCP rise or fall together in real trial operations.

  2. 8:00

    Patient Safety In Practice

    Consent, AE and SAE pathways, deviations with safety impact, and when escalation happens too late.

  3. 18:00

    Data Integrity At Source

    ALCOA+, source records, eSource risk, backdating, and why audit trails are less forgiving than people.

  4. 28:00

    GCP As Operating System

    Delegation, training, supervision, and the logic behind common inspection findings.

  5. 37:00

    How Failures Cascade Quickly

    See how small disconnects across people, process, and systems become larger quality problems.

  6. 45:00

    Risk-Based Controls That Work

    Map critical processes, review trends, and build CAPAs that hold up after the meeting ends.

  7. 54:00

    Three-Pillar Review Recap

    Apply the review to one live study, prioritize actions, then close with Q&A and next steps.

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