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The Biggest Compliance Risks in AI-Enabled Clinical Trials

  • 61 minutes
  • 32 slides
What we'll cover
  • 0:00 Where AI Touches Trials
  • 8:00 Risk Starts With Intended Use
  • 17:00 Validation Beyond Vendor Demos
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What you'll take away

Practical shifts you can apply this week

  • Identify The Highest Exposure

    Identify the AI use cases in clinical trials that create the highest compliance exposure.

  • Evaluate Tool Classification

    Evaluate whether an AI tool should be treated as a GxP-relevant system or decision support function.

  • Compare Risk Across Controls

    Compare the compliance risks of model design, data inputs, human oversight, and vendor claims.

  • Diagnose Weak Control Gaps

    Diagnose weak controls in validation, documentation, monitoring, and change management for AI-enabled workflows.

  • Draft A Governance Checklist

    Draft a practical escalation and governance checklist for high-risk AI deployments in trials.

Agenda

What we'll cover

  1. 0:00

    Where AI Touches Trials

    Common use cases across protocol design, recruitment, site selection, data review, and safety.

  2. 8:00

    Risk Starts With Intended Use

    How to define what the tool may do, who reviews it, and what happens when it is wrong.

  3. 17:00

    Validation Beyond Vendor Demos

    What real evidence looks like in your workflow, population, and edge cases.

  4. 29:00

    Data Integrity And Provenance

    Traceability for inputs, outputs, overrides, lineage, and ALCOA+ implications.

  5. 39:00

    Consent, Privacy, And Fairness

    Where participant data use, transparency, and subgroup performance create exposure early.

  6. 47:00

    Vendors, Contracts, And Change

    Due diligence, responsibility splits, version control, and why risk does not vanish in an SLA.

  7. 54:00

    Inspection-Ready Governance Moves

    A practical checklist for ownership, documentation, escalation, and go or no-go decisions.

  8. 59:00

    Recap And Live Q&A

    Review the risk checklist, then ask questions you would rather catch now than during an inspection.

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